Reach Online Pharmacy

Xenical

£34.99

  • More Affordable Alternative → Orlistat
  • Helps reduce the amount of fat your body absorbs
  • Should be taken alongside a healthy diet and regular exercise programme
SKU: 460711000001105 Category:

Order Xenical Weight Loss Pills Online

You can request to order Xenical (Orlistat) weight loss medication online from Reach Online Pharmacy, a UK-registered online pharmacy and doctor service. Once you complete your medical assessment and place your order, it will be reviewed by one of our GMC-registered doctors. If approved, our pharmacy team will dispense and dispatch your medication to your chosen address via Royal Mail, with delivery options including next working day delivery.

What is Xenical?

Xenical 120mg Capsules – Weight Loss Treatment

Xenical capsules are a prescription weight loss treatment for adults with a BMI over 30. They may also be suitable for people with a BMI over 28 who have weight-related conditions, such as high blood pressure.

Xenical is recommended to support weight loss while you are actively working towards a healthier lifestyle through diet, exercise, and other weight management strategies. For best results, treatment should always be combined with a low-fat diet and regular physical activity.

Xenical is a branded medicine containing orlistat 120mg as its active ingredient. A more affordable generic orlistat 120mg is also available through our Reach Online Pharmacy doctor service. In addition, lower strength orlistat 60mg medicines are available over the counter, such as Alli 60mg and Orlos 60mg.

How Xenical 120mg Works

Xenical 120mg works by blocking around 30% of the dietary fat you consume from being digested. This undigested fat is not absorbed by the body and instead passes through your digestive system naturally during bowel movements.

The active ingredient, orlistat, works by stopping an enzyme called lipase in your digestive tract from breaking down fat. As a result, the fat remains undigested and is removed from the body.

By preventing fat absorption, Xenical helps reduce your overall calorie intake, making it easier to maintain a calorie deficit — which is essential for weight loss. However, Xenical on its own is not enough to achieve weight loss. To lose weight, you must burn more energy than you take in from food and drinks.

Xenical simply helps tip the balance by lowering your daily calorie intake, but it is still important to:

  • Follow your recommended low-fat diet

  • Stick to a regular exercise plan

  • Maintain other healthy lifestyle habits

How effective is Xenical?

Xenical can help reduce fat absorption by around 25–33%. Clinical studies have shown that patients taking Xenical are twice as likely to lose more than 10% of their body weight over a year compared to those relying on diet alone.

However, it’s important to remember that diet and exercise remain essential for achieving the best results while using Xenical. Combining the medication with a balanced, low-fat diet and regular physical activity will give you the greatest chance of successful long-term weight loss.

How to Take Xenical

Take Xenical exactly as prescribed by your doctor. The usual dose is one 120mg capsule taken immediately before, during, or up to one hour after a meal, up to three times a day. You should not take more than three capsules in a single day.

Xenical works by reducing the amount of fat your body absorbs. If you eat a meal that contains no fat, you do not need to take a dose. However, be mindful that even healthy foods often contain some fat.

If you are unsure about your diet plan while using Xenical, refer to our guidance on ‘How to get the best results from orlistat’ or speak with one of our healthcare professionals for personalised advice.

Treatment Duration

Your doctor will usually review your progress with Xenical after 12 weeks of treatment. If orlistat has been effective and you have achieved a noticeable weight reduction after three months, your prescription may be continued for up to one year.

After this period, your GP will reassess your condition and decide whether it is appropriate for you to continue treatment with orlistat.

Key Information – Xenical 120mg Capsules

Detail Information
Dose One capsule immediately before, during, or up to one hour after main meals, up to three times daily
Type of Medicine Lipase inhibitor – weight loss
Mechanism Reduces fat absorption from meals by up to 30%
Active Ingredient Orlistat 120mg
Price From £29.99
Possible Side Effects Flatulence, oily stools, increased bowel motions, urgent bowel motions

Xenical Prices

Quantity Price
42 Capsules £29.99
84 Capsules £44.50
168 Capsules £87.99
252 Capsules £130.50

Alternative Treatments

As with any medicine, some people may find that Xenical is not the most suitable treatment for their weight loss plan.

Other prescription weight loss options available in the UK include the appetite suppressant injections Wegovy and Saxenda. These treatments come as pre-filled pens that are injected into the upper arm, thigh, or abdomen.

  • Wegovy is injected once weekly

  • Saxenda is injected once daily

These options may be considered if you experience side effects with Xenical or if your doctor feels a different approach is more appropriate. Like Xenical, Wegovy and Saxenda are prescription-only medicines and are supplied only after a completed online medical assessment through Reach Online Pharmacy.

Xenical side effects

Every medication can cause side effects, and Xenical is no different. However, sticking to a low-fat diet can greatly reduce the likelihood and severity of these side effects.

Common side effects of Xenical

  • Fatty or oily stools

  • Urgent need to use the toilet

  • Passing stools more frequently

  • Oily discharge from the rectum (which may leave oily spots on your underwear)

  • Flatulence (wind)

  • Stomach pain or discomfort

  • Headaches

The majority of these side effects are mild and usually occur at the start of treatment. They often subside as you continue treatment alongside a healthy diet.
Some of these side effects are more likely to happen if you take a dose with a very high-fat meal.

What to Eat When Taking Xenical

Xenical treatment should always be combined with a low-calorie, low-fat diet to achieve the best results. It is important to spread your daily fat intake evenly across your three main meals, rather than consuming most of your fat in one meal.

This approach helps reduce the chance of side effects such as oily stools and urgent bowel movements, while also supporting steady and sustainable weight loss.

For more guidance, you can refer to our article on the ‘orlistat diet’, which explains how to optimise your results while taking Xenical (orlistat).

Who Can Use Xenical

Xenical 120mg capsules are usually prescribed for adults with:

  • A BMI over 30, or

  • A BMI over 28 with an additional weight-related condition, such as type 2 diabetes, high cholesterol, or high blood pressure

Your suitability for Xenical will be assessed by a qualified UK prescriber through our Reach Online Pharmacy online consultation service before treatment is approved.

What Is the Difference Between Xenical and Orlistat?

Xenical is the branded version of orlistat. Both contain the same active ingredient (orlistat 120mg) and work in the same way to reduce fat absorption from your meals.

The main difference is that Xenical is a branded medicine, while orlistat is the generic version, which is usually more affordable but equally effective.

What Is the Difference Between Orlistat / Xenical and Alli?

Alli is the over-the-counter version of orlistat, available without a prescription. It contains 60mg of orlistat, which is half the strength of the prescription-only versions Xenical and generic orlistat (120mg).

While Alli works in the same way to reduce fat absorption, it is generally recommended for people who are overweight rather than clinically obese, and who are looking for a lower-strength starting option.

Can You Buy Xenical Online or Over the Counter?

Xenical cannot be bought over the counter in the UK — it is a prescription-only medicine.

At Reach Online Pharmacy, our UK-registered doctors can prescribe Xenical online following a simple consultation. You’ll just need to complete an online medical assessment, which allows our doctors to check whether Xenical is suitable for you. If approved, our pharmacy team will dispense and deliver your medication directly to your chosen address.

Although Xenical is not available over the counter, you can buy a lower-strength version of orlistat (Alli 60mg) without a prescription. This can be purchased after a short consultation with a pharmacist or ordered from our online pharmacy shop.

Treatment Comparison

Saxenda Xenical Orlistat Mysimba
Ingredient Liraglutide Orlistat 120mg Orlistat 120mg Naltrexone/Bupropion
Mechanism Regulates appetite Reduces fat absorption Reduces fat absorption Regulates appetite
Dose Injected once daily One three times daily with meals One three times daily with meals Gradually increased to 4 tablets daily

Before taking any medication, it is important to read the Patient Information Leaflet.

Precautions

Medical conditions and Xenical

Xenical is not suitable for everyone.
You should not take Xenical if you have:

  • An allergy to orlistat or any of the ingredients in Xenical

  • The liver disorder cholestasis

  • Chronic malabsorption syndrome (a condition where your body cannot absorb nutrients properly)

Taking Xenical with other medicines

  • Medicine interactions: Xenical can affect the way some medicines work, such as warfarin and levothyroxine. Always check the patient information leaflet or speak to your doctor or pharmacist for advice. The dose of some medicines may need to be adjusted if you lose weight.

  • Contraceptive pill: Xenical can sometimes cause severe diarrhoea, which may reduce the effectiveness of the contraceptive pill. If this happens, use an additional form of contraception (e.g. condoms).

  • Vitamins: Xenical can reduce the amount of certain fat-soluble vitamins your body absorbs. Your doctor may recommend taking a daily multivitamin supplement while on treatment.

Xenical in Pregnancy and Breastfeeding

  • Pregnancy: Xenical capsules should not be used during pregnancy. There is limited safety data, and it may reduce the absorption of fat-soluble vitamins, which could affect the nutrient supply to the developing fetus.

  • Breastfeeding: It is not known if orlistat passes into breast milk. Therefore, Xenical should not be used by breastfeeding mothers.

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